Detection of Action Potentials In Vitro by Changes in Refractive Index
نویسندگان
چکیده
The detection of individual action potentials in nerve cells via intrinsic optical signals could open a new modality for the analysis of cellular properties in spatially extended cells and emergent properties in networks of neurons. Here we review the experimental evidence for the detection of changes in intrinsic optical properties, i.e., changes in optical refractive index, that covary with changes in the transmembrane voltage.
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